Open AccessCHANGES IN THE CRYSTAL STRUCTURE OF POWDER BENZYLPENICILLIN SODIUM SALT UNDER THE INFLUENCE OF A HIGH-INTENSITY PULSED MAGNETIC FIELD
Author(s) -
N.A. Rodenko,
V.A. Gluschenkov,
K.A. Osintsev,
S.V. Konovalov,
I.A. Belyaeva,
T.I. Vasilyeva
Publication year - 2022
Publication title -
izvestiâ samarskogo naučnogo centra rossijskoj akademii nauk
Language(s) - English
Resource type - Journals
ISSN - 1990-5378
DOI - 10.37313/1990-5378-2022-24-1-30-36
Subject(s) - benzylpenicillin , sodium , salt (chemistry) , materials science , chemistry , crystal structure , diffraction , crystallography , nuclear magnetic resonance , antibiotics , biochemistry , optics , organic chemistry , metallurgy , penicillin , physics
To understand the nature of the influence of a pulsed magnetic field on the antibacterial properties of benzylpenicillin sodium salt against Escherichia coli M-17 bacteria, an exploratory study of benzylpenicillin sodium salt powder under X-ray radiation was performed. Corresponding diffraction patterns were obtained, reflecting the changes occurring in the antibiotic molecule after the impact of a PMF on the drug. The fact of disorganization of the crystal lattice of powdered benzylpenicillin under the influence of a pulsed magnetic field with a strength of (2÷7) 106 A/m has been established.