Open AccessLoss of Fingerprints as a Side Effect of Capecitabine Therapy: Case Report and Literature Review
Author(s) -
Jian Zhao,
Xia Zhang,
Xiaonan Cui,
Di Wang,
Bin Zhang,
Ban Li-ying
Publication year - 2020
Publication title -
oncology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 57
eISSN - 1555-3906
pISSN - 0965-0407
DOI - 10.3727/096504019x15605078731913
Subject(s) - capecitabine , medicine , hair loss , side effect (computer science) , surgery , erythema , weight loss , dermatology , cancer , colorectal cancer , obesity , computer science , programming language
Hand‐foot syndrome (HFS) is the main side effect of capecitabine and affects the compression zones of the body such as the palms and soles, causing numbness, paresthesias, skin swelling or erythema, scaling, chapping, hard nodule-like blisters, and severe pain. Loss of fingerprints is also observed in some cases. Severe cases of HFS are common in the review of clinical reports. However, loss of fingerprints has not received significant attention. Two reported cases of loss of fingerprints in The New England Journal of Medicine and The BMJ have drawn attention to this side effect of capecitabine. Loss of fingerprints has a serious impact on patients’ daily life, especially on personal identification. This report describes a patient who lost her fingerprints during the early stage of chemotherapy. Our aim is to draw the medical profession’s attention to this problem.