Open AccessDetermination of distearyl dimethyl ammonium chloride in textiles by reversed-phase and normal-phase liquid chromatography-electrospray ionizationtandem mass spectrometry
Author(s) -
Yongcheng Ding,
Xiaoping Shen,
Xiaoqiong Wu,
Linlin Wu,
Xun Cao
Publication year - 2011
Publication title -
sepu/chinese journal of chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.171
H-Index - 19
eISSN - 1872-2059
pISSN - 1000-8713
DOI - 10.3724/sp.j.1123.2011.00507
Subject(s) - chromatography , chemistry , electrospray ionization , mass spectrometry , electrospray , extraction (chemistry) , ammonium chloride , detection limit , solid phase extraction , selected reaction monitoring , solvent , tandem mass spectrometry , liquid chromatography–mass spectrometry , organic chemistry
A method of reversed-phase (RP)/normal-phase (NP)-liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) was developed for the determination of distearyl dimethyl ammonium chloride (DSDMAC) in textiles. The DSDMAC in textile was extracted by ultrasound-assisted extraction using methanol as extraction solvent under the conditions of 70 degrees C and 420 W within 30 min. The three quaternary ammonium compounds of DSDMAC were detected by LC-MS/MS in the selective reaction monitoring (SRM) mode. The limits of detection (LODs) (S/N = 3) of DSDMAC detected by RPLC-MS/MS and NPLC-MS/MS based on an amino-column were 0.1 mg/kg and 0.01 mg/kg, respectively. The recoveries of DSDMAC spiked in the eight different types of blank fabrics ranged from 85.5% to 103% with the relative standard deviations (RSDs) of 4.18% - 12.8% (n = 5) by RPLC-MS/MS method. Five laboratories were invited to take part in the validation of the method, and the RSDs of inter-lab were 7.3% - 9.4% on two reference samples. The method is fast, accurate and reproducible, and can meet the demands of the determination of DSDMAC in textiles.