Advances of development of phage display systems | Zendy

Fanmei Meng | Zendy; Chaohui Zhang | Zendy; Yuncan Ai | Zendy

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Advances of development of phage display systems

Author(s) -

Fanmei Meng,

Chaohui Zhang,

Yuncan Ai

Publication year - 2011

Publication title -

hereditas (beijing)

Language(s) - English

Resource type - Journals

ISSN - 0253-9772

DOI - 10.3724/sp.j.1005.2011.01113

Subject(s) - phage display , computational biology , biology , selection (genetic algorithm) , genome , genetics , bacteriophage , synthetic biology , gene , computer science , escherichia coli , artificial intelligence , antibody

The phage display technology (PDT) was unique in genetic engineering and recombinant expression. The phage display systems (PDS) were platforms (kits) composed of genetic modified phages, helper phages, and host bacteria. This review concisely summarized the development of four types of PDS, based on M13, λ, T4, and T7 phages, in terms of phage molecular genetics and genetic (gene or genome) engineering. We addressed on the key components and their genetic (genomic) engineering for modifications, the technical features of different anchors, and the development progress and selection reference of those different kits.

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