Open AccessProgresses on thyroid hormone responsive spot 14 (<I>THRSP</I>) gene in chickens and ducks
Author(s) -
Kai Zhan,
Ning Yang,
Guiyun Xu,
Yue-Ying XU,
Rui-Hong ZHAO
Publication year - 2009
Publication title -
hereditas (beijing)
Language(s) - English
Resource type - Journals
ISSN - 0253-9772
DOI - 10.3724/sp.j.1005.2009.00131
Subject(s) - biology , gene , lipogenesis , gene isoform , gene expression , complementary dna , endocrinology , genetics , microbiology and biotechnology
Thyroid hormone responsive spot 14 (THRSP), expressed in lipogenic tissues, is suggested as a transcription factor to regulate gene expression of rate-limiting enzymes in lipogenesis. Two THRSP isoforms, THRSPa and THRSPb, were detected at cDNA levels in chickens and ducks. Chicken THRSPa was speculated to be associated with growth development and lipid metabolism because of significant correlation between the indels in the coding region of THRSPalpha and growth, as well as abdominal fat traits of chickens. The differences of THRSP structure and expression between chickens and ducks were reviewed. Furthermore, polymorphism and genetic effects of THRSP gene in chickens and ducks were analyzed.
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