Open AccessDisease Severity, Clinical Characteristics and Outcome of Patients Hospitalized with Novel Coronavirus Disease at a Tertiary Care Hospital, Rawalpindi
Author(s) -
Muhammad Shabir,
Shazia Nisar,
Zobia Urooj,
Uzma Qayyum,
Fozia Fatima,
Zahid Hussain
Publication year - 2021
Publication title -
life and science
Language(s) - English
Resource type - Journals
eISSN - 2708-2970
pISSN - 2521-0475
DOI - 10.37185/lns.1.1.180
Subject(s) - medicine , disease , case fatality rate , diabetes mellitus , intensive care unit , severity of illness , kidney disease , mortality rate , intensive care medicine , pediatrics , epidemiology , endocrinology
Objective: To describe the clinical characteristics, signs & symptoms, disease severity, and outcome of patientsadmitted with novel coronavirus infection.Study Design: Comparative cross-sectional study.Place and Duration of Study: The study was conducted in the Department of Medicine of Pak-Emirates Militaryst th Hospital, (PEMH), Rawalpindi from May 1 , 2020 to June 30 , 2020.Materials and Methods: Patients hospitalized with novel corona virus infection during the study period wereprospectively enrolled in this study. Patients at least 15 years and above, either gender, hospitalized withconfirmed diagnosis of covid-19 (SARS-CoV-2) were eligible to be enrolled. The study outcomes includeddisease presentation, severity at time of reporting, admission to critical care or intensive care unit andmortality. Patients were identified as mild, moderate, severe and critical in accordance with World HealthOrganization guidelines, based on symptom severity, laboratory and imaging findings.Results: There were 400 hospitalized patients with confirmed SARS-CoV-2, out of which 51 (12.8%) werefemales, while 349 (87.3%) were males with overall mean age of 48.45±16.2 years. There were 300 (75.0%)patients with mild disease severity, while 65 (16.3%), 20 (5.0%) and 15 (3.8%) with moderate, severe and criticaldisease condition, respectively. The number of patients died were 22, with fatality rate of 5.5%. Age andpresence of comorbidities (cardiac disease, diabetes, hypertension, pulmonary disease, kidney disease) weresignificantly associated with disease severity and death due to novel coronavirus infection.Conclusion: Patients with older age, diabetes, hypertension, pulmonary disease, kidney disease were at higherrisk of developing severe disease condition and death due to novel coronavirus infection.