Recurrent Unresectable Aggressive Fibromatosis of Neck

Aggressive fibromatosis or desmoid tumors are classified as low grade, locally aggressive sarcomas with high propensity to recur and are lacking a clear census on management of recurrent-surgically in excisable tumors. We report here the case of a 27yrs old male with aggressive fibromatosis that recurred following a surgical excision, and resulted in hamper-ing the quality of life. The disease was managed using cytotoxic chemotherapy with doxoru-bicin, resulting in significant clinical and radiological response. It was followed by mainte-nance regimen using a less aggressive approach with non-steroidal anti-inflammatory drugs such as celecoxib that resulted in further clinical response at 2 months follow up. Therefore, the therapy was further continued.