Open AccessLimited Wedge Resection of a Duodenal Gist in a Patient with Intermittent Melena
Publication year - 2021
Publication title -
liaquat national journal of cancer care
Language(s) - English
Resource type - Journals
eISSN - 2789-0120
pISSN - 2789-0112
DOI - 10.37184/lnjcc.2789-0112.2.3
Subject(s) - melena , medicine , gist , duodenum , wedge resection , upper gastrointestinal bleeding , lesion , epigastric pain , biopsy , pancreaticoduodenectomy , endoscopic ultrasound , differential diagnosis , gastroenterology , radiology , endoscopy , surgery , pancreas , vomiting , stromal cell , resection , pathology
Gastrointestinal Stromal Tumors account for 1% - 2% of all gastrointestinal (GI) tract tumors. Among GISTs, duodenal localization occurs in less than 5% and usually presents with upper GI bleeding. A 45-year-old man presented in the outpatient department with complaints of epigastric discomfort, intermittent melena and undocumented weight loss for the preceding 3 months. Initial upper GI endoscopy showed mild duodenitis and no other upper GI pathology. For unexplained symptoms, a CT Scan was performed which demonstrated a well-defined solid lesion along the second part of the duodenum. An endoscopic ultrasound (EUS)-guided biopsy of a subepithelial lesion at D2 was performed. Immunohistochemistry findings were suggestive of GIST. Wedge resection of the duodenal mass was done.Duodenal GIST should be considered as a differential in cases of GI bleeding when other differentials have been ruled out. Limited resection of duodenal GIST should be considered over pancreaticoduodenectomy, in case of small size tumors.