Open AccessCombined Surgical/Interventional-Radiological Cytoreduction in a Patient with Disseminated Highly Differentiated Neuroendocrine Ileal Tumor
Author(s) -
Н. А. Перегудов,
Л. А. Фалалеева,
Olga Sergeeva,
А. А. Маркович,
Б. И. Долгушин
Publication year - 2021
Publication title -
onkologičeskij žurnal: lučevaâ diagnostika, lučevaâ terapiâ
Language(s) - English
Resource type - Journals
eISSN - 2713-167X
pISSN - 2587-7593
DOI - 10.37174/2587-7593-2021-4-2-92-100
Subject(s) - medicine , radiological weapon , neuroendocrine tumors , radiology , stage (stratigraphy) , surgery , paleontology , biology
A combined approach to cytoreduction in a patient with a neuroendocrine tumor G1 the ileum with multiple bilobar metastases G2 in the liver, originally considered as a candidate only for drug therapy, has been demonstrated. The first stage was laparoscopic resection of the ileocecal segment of the intestine, followed by interventional radiological intervention — a two-stage selective transarterial oil chemoembolization of the liver with bleomycin. As a result, 90 % cytoreduction, suppression of clinical manifestations, normalization of chromogranin A and serotonin were achieved. The patient continues to be observed without signs of progression for more than 4 years from the moment of diagnosis. It is shown that multidisciplinary treatment of patient with timely inclusion of interventional-radiological interventions allows achieving long-term favorable results in patients with advanced stage of disease.