Open AccessDiagnostic challenges of oral leishmaniasis: unusual presentation of two cases
Author(s) -
André Gebrim Matias,
Vinícius Gonçalves de Souza,
Eduardo Carreira Marcório,
Damilys Joelly,
Santos Souza,
Tatiana Santos Araújo,
Aparecida De,
Lourdes Carvalho,
Leandro Raphael N. de. Paula,
Valbert Nascimento Cardoso,
Carla Silva,
S. L. V. De Miranda,
André Gebrim,
Abigair Duarte Matias,
Tatiana Maria Palmeira dos Santos,
Aparecida Gomes de Araújo,
Aída Luz Villa,
Paula Ludimila,
Carla M. P. Cardoso,
S. A. Silva
Publication year - 2021
Publication title -
international journal of developmental research
Language(s) - English
Resource type - Journals
ISSN - 2230-9926
DOI - 10.37118/ijdr.22136.06.2021
Subject(s) - medicine , leishmaniasis , dermatology , histopathology , disease , pathology , visceral leishmaniasis , differential diagnosis , medical diagnosis
Leishmaniasis is a non-contagious infectious disease and has a broad spectrum of clinical forms. Isolated oral mucosal leishmaniasis is rare and challenges clinicians and pathologists. We report two cases of oral leishmaniasis manifested as ulcerative growth on the palate and tongue nodule. Histopathological analysis was performed and the final diagnosis was made with the visualization of amastigote-like structures. Both cases had unusual clinical manifestations and many differential diagnoses were considered, including syphilis, paracoccidioidomycosis and mesenchymal or epithelial neoplasms. The broad spectrum of clinical manifestations and the often-inconclusive findings in histopathology reinforce the importance of clinicopathological correlation in diagnosis of leishmaniasis.