Open AccessEffect of Some Strains of Lactic Acid Bacteria and Their Mixture on the Level of Fats and Cholesterol in Albino Rats (Rattus norvegicus) Male with Hypothyroidism Induced Using Carbimazole
Author(s) -
Elham Kadhim Nasser,
Kithar Rasheed Majeed,
Hayder I. Ali
Publication year - 2021
Publication title -
maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.144
H-Index - 2
eISSN - 2520-0860
pISSN - 1814-5868
DOI - 10.37077/25200860.2021.34.1.12
Subject(s) - very low density lipoprotein , cholesterol , lipoprotein , carbimazole , lactic acid , high density lipoprotein , endocrinology , low density lipoprotein , lactobacillus acidophilus , medicine , chemistry , food science , biology , bacteria , probiotic , thyroid , genetics , graves' disease
Fortified milk containing Lactobacillus plantarum, L. casei, and L. acidophilus isolates and their mixture were used in dosing the male albino rats at an age of 9-12 weeks at an average of 23 g with induced hypothyroidism at a concentration of 0.6 g.kg-1 of carbimazole. Total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low-density lipoprotein (VLDL) were estimated. The results showed a significant increase in the level of triglycerides (TG), cholesterol and triglycerides. Low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL), with a significant decrease in the level of high-density lipoprotein (HDL) in infected male mice, compared to the control sample, and upon dosing with liquid milk fortified, it returned to its normal level without significant differences from the control group.