Open AccessANALYSIS OF FUNCTIONAL CHANGES IN THE RODENTS CENTRAL NERVOUS SYSTEM AT A SINGLE UPTAKE OF DEPLETED URANIUM OXIDE MIXED WITH WATER
Author(s) -
Dmitry Gerasimov
Publication year - 2017
Publication title -
toksikologičeskij vestnik
Language(s) - English
Resource type - Journals
ISSN - 0869-7922
DOI - 10.36946/0869-7922-2017-1-42-46
Subject(s) - uranium , depleted uranium , central nervous system , chemistry , reflex , striatum , neurotransmitter , neuroscience , dopamine , biology , materials science , metallurgy
Behavioral responses in experimental animals were studied in an experiment after a single uptake of aqueous solution of mixed depleted uranium oxide using standard techniques. The experimental research showed pronounced integrative functions disorders in the rodents brain which are associated with impacts of uranium compounds on structures providing coordination of motor acts, on conditioned reflex activity as well as anxiety-phobic and emotional state of animals. Temporary neurotoxic effects of depleted uranium may be a result of both direct oxidant activity impact of uranium compounds on neurons and consequence of their effect on the neurotransmitter metabolism .