Open AccessMesoporous silica nanoparticles for drug delivery—Recent advances
Publication year - 2019
Publication title -
advanced applied materials
Language(s) - English
Resource type - Journals
ISSN - 2003-0789
DOI - 10.36822/adv.app.mater.201903
Subject(s) - mesoporous silica , pharmaceutics , drug delivery , nanotechnology , bioavailability , nanoparticle , drug , mesoporous material , materials science , chemistry , pharmacology , medicine , catalysis , biochemistry
Mesoporous silica nanoparticles (MSNs) have been attracting great attention for the potential biomedical applications in the last decades. Due to the unique properties, such as tunable mesoporous structure, huge surface area, large pore volume, as well as the functional ability of surface, MSNs exhibit high loading capacity for therapeutic active pharmaceutical ingredients (APIs) and controllable release behavior. In this review, the applications of MSNs in pharmaceutics improving the bioavailability, reducing toxicity of loaded drugs, increasing cellular targeted delivery ability and recent advances in drug delivery are summarized.