Open AccessAlbumin-Fibrinogen Ratio in rheumatoid arthritis and its relation to disease severity and radiographic progressive changes
Author(s) -
Gihan O Taher,
Fayza A Elhamdy,
Aisha Alfituri,
Awad M Alhasy
Publication year - 2022
Publication title -
open journal of radiology and medical imaging
Language(s) - English
Resource type - Journals
ISSN - 2583-1534
DOI - 10.36811/ojrmi.2022.110042
Subject(s) - fibrinogen , rheumatoid arthritis , medicine , synovitis , albumin , gastroenterology , radiography , surgery
Aim of the work: To evaluate the relationship between albumin-fibrinogen ratio (AFR) and radiographic changes in rheumatoid arthritis (RA) Patients and Methods: 50 rheumatoid patients and 30 control subjects were collected for the study, they were investigated for RF, Anti CCP, ESR, CR, fibrinogen and albumin. Also, they were subjected to x ray and MRI examinationResults: There was significant increase in laboratory parameters and increase in albumin fibrinogen ratio in rheumatoid patients as compared to healthy control subjects. Also, there was positive correlation of the ratio with X ray and MRI score for synovitis and bone destructionConclusion: AFR may be easily, rapidly detected and prognostically useful markers of ongoing inflammation and joint affection correspondingly to radiological findings.Keywords: Rheumatoid arthritis; Albumin-fibrinogen ratio; MRI