Open AccessOvercoming Immune Depletion is the Main Goal of Developing New Therapies
Author(s) -
Ricardo Gobato,
Abhijit Mitra
Publication year - 2021
Publication title -
open journal of radiology and medical imaging
Language(s) - English
Resource type - Journals
ISSN - 2583-1534
DOI - 10.36811/ojrmi.2021.110023
Subject(s) - immunotherapy , immune system , medicine , discontinuation , cancer , cancer treatment , cancer immunotherapy , immunology , intensive care medicine
In recent years, immunotherapy has revolutionized the treatment of cancer; However, inflammatory reactions in healthy tissues often have side effects that can be serious and lead to permanent discontinuation of treatment. This toxicity is not yet well understood and is a major obstacle to the use of immunotherapy. When the immune system is so severely activated, the resulting inflammatory reaction can have detrimental effects and sometimes serious damage to healthy tissue. We wanted to know if there was a difference between an optimal immune response that aims to kill cancer and an unwanted response that could affect healthy tissue. Identifying the distinctive elements between these two immune responses allows the development of new, more effective and less toxic therapeutic approaches.Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management