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Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells
Author(s) -
Alireza Heidari,
Elena Locci,
Silvia Raymond
Publication year - 2021
Language(s) - English
DOI - 10.36811/jca.2021.110030
Subject(s) - inflammasome , cancer , medicine , inflammation , melanoma , cancer research , tumor microenvironment , cancer cell , immunology
Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management

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