Open AccessESTIMATION OF THE POSSIBILITY OF WASTEWATER PURIFICATION FROM PHARMACEUTICAL PREPARATIONS BY RADIATION METHOD
Author(s) -
Zhanna B. Lyutova,
Natalya A. Orekhova,
Anastasia A. Yamshchikova,
I. V. Yudin
Publication year - 2021
Publication title -
izvestiâ sankt-peterburgskogo gosudarstvennogo tehnologičeskogo instituta (tehničeskogo universiteta)
Language(s) - English
Resource type - Journals
ISSN - 1998-9849
DOI - 10.36807/1998-9849-2021-58-84-27-32
Subject(s) - aqueous solution , chemistry , ketoprofen , radiolysis , chromatography , ionizing radiation , decomposition , wastewater , irradiation , organic chemistry , physics , nuclear physics , engineering , waste management
To assess the possibility of using radiation purification of aqueous solutions from contained pharmacological preparations by spectrophotometry, high-performance liquid chromatography and chemical analysis, the effect of the absorbed dose of ionizing radiation on the concentration of analytes in solutions was studied. The values of the radiation-chemical yield of destruction of the investigated pharmaceutical preparations, the formation of peroxide products of radiolysis were determined, and the values of absorbed doses sufficient for the complete decomposition of the substances under consideration were calculated. It was shown that at initial concentrations of ketoprofen of 1,1•10-4 M and diclofenac of 0,5•10-4 M, the values of absorbed doses required for their complete decomposition are 2,4 kGy and 0,85 kGy, respectively. The obtained values indicate the possibility of using radiation technology for the purification of aqueous solutions from those pharmaceutical preparations. Further research can clarify the necessary doses for sufficient destruction of various groups of drugs in concentrations found in wastewater