Open AccessADMISSION VARIABLES ASSOCIATED WITH INDEPENDENT AMBULATION AT TIME OF DISCHARGE FROM A COMPREHENSIVE STROKE UNIT
Author(s) -
Yuriy Flomin,
V. H. Hurianov,
Л. И. Соколова
Publication year - 2021
Publication title -
wiadomości lekarskie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.133
H-Index - 14
eISSN - 2719-342X
pISSN - 0043-5147
DOI - 10.36740/wlek202108112
Subject(s) - medicine , logistic regression , confidence interval , univariate analysis , odds ratio , stroke (engine) , univariate , multivariate analysis , multivariate statistics , cohort , statistics , mechanical engineering , mathematics , engineering
The aim: To identify admission variables associated with Functional Ambulation Classification (FAC) 1 to 4 (unable to walk without assistance) at time of discharge (dFAC<5) from a comprehensive stroke unit (CSU). Materials and methods: Patients admitted to CSU at Oberig Clinic, Kyiv, Ukraine, August 01, 2012 to July 31, 2018, were screened for study selection criteria. Association of qualifying patients’ data with FAC score at CSU discharge was retrospectively assessed by univariate and multivariate logistic regression, odds ratios (OR) and 95% confidence intervals (95% CI) using MedCalc v. 19.1. Results: The study cohort (442 of 492 admitted patients) had median age: 65.8 years, gender: 43% female, stroke-type: 84% ischemic strokes, median baseline NIHSS total score: 10. Estimated time from stroke onset to CSU admission was from less-than-24-hours to over-180-days. The univariate logistic regression analysis, revealed 28 variables significantly (p<0.05) related to dFAC<5; while in multivariate analysis only 4 admission variables were significantly (p<0.05) associated with dFAC<5: age (OR= 1.07; 95% CI 1.03-1.10, on average, for each additional year, p<0.001), baseline NIHSS score (OR= 1.15; 95% CI 1.08-1.22, on average, with a 1-point increase in the total score, p<0.001), initial FAC score (OR= 0.40; 95% CI 0.31–0.52, on average, with a 1-point decrease in the score, p<0.001), and very late CSU admission (over 180 days; OR= 5.7; 95% CI 1.9–17.1, p=0.002). Conclusions: Four admission variables may be independently associated with dFAC<5 and provide opportunity for improving CSU outcomes and mitigating risk for inability to ambulate without assistance after CSU discharge.