Open AccessFEATURES OF VIOLATIONS OF THE STATE OF THE VAGINAL ECOSYSTEM IN PREGNANT WOMEN WITH BACTERIAL VAGINOSIS
Author(s) -
Ирина Николаевна Щербина,
Iryna Yu Plakhotna
Publication year - 2021
Publication title -
wiadomości lekarskie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.133
H-Index - 14
eISSN - 2719-342X
pISSN - 0043-5147
DOI - 10.36740/wlek202103114
Subject(s) - bacterial vaginosis , dysbiosis , gardnerella vaginalis , biofilm , vaginitis , bacteria , microbiology and biotechnology , vagina , biology , pathogenic bacteria , obstetrics , physiology , medicine , gynecology , microbiome , bioinformatics , surgery , genetics
The aim: To assess the condition of the vaginal ecosystem in pregnant women with BV.Materials and methods: The main group consisted of 60 pregnant women with BV in the II trimester. The bacterioscopic examination, of vaginal smears was carried out. DNAdiagnostics of the microbial spectrum of vaginal contents was performed. Bacteria with biofilm were visualized by fluorescence hybridization in situ.Results: Biofilms were found in 25 women (41.65%) of the main group, the main component of which was bacteria belonging to the Gardnerella cluster at a concentration of 7.9 ± 0.13 log CFU/ g. Atopobium vagine cluster bacteria gave positive hybridization signals in more than half of the patients and amounted to 6.8 ± 0.15 lg CFU / g. In addition, Snethia spp. was determined as a part of the biofilm at a concentration of 5.8 ± 0.3 lg CFU / g.Conclusions: Thus, the use of the proposed treatment regimen for women with vaginal dysbiosis led to the elimination of pathogenic and conditionally pathogenic microflora.However, the effectiveness of treatment in 5 cases was lower than expected, which indicates the emergence of bacterial resistance.