Open AccessMORPHOLOGICAL CHANGES OF THE ENDOMETRIUM IN HYPERPLASTIC PROCESS IN WOMEN OF REPRODUCTIVE AGE
Author(s) -
Tetiana V. Vereshchahina,
А. V. Boychuk,
Yuliia B. Yakymchuk,
Iryna M Nikitina,
Tetiana V. Datsko
Publication year - 2021
Publication title -
wiadomości lekarskie
Language(s) - English
Resource type - Journals
eISSN - 2719-342X
pISSN - 0043-5147
DOI - 10.36740/wlek202103102
Subject(s) - atypia , endometrium , hyperplasia , gynecology , physiology , endometrial hyperplasia , medicine , etiology , pathogenesis , obstetrics , pathology
The aim: To conduct a morphological study of endometrial tissue to identify changes characteristic of viral lesions to develop improved antirelapse treatment of HPE in womenof reproductive age.Materials and methods: We surveyed 90 patients of the gynecological department who sought medical for hyperplastic processes of the endometrium in reproductive age.All women underwent hysteroscopy, the resulting material was subjected to morphological examination.Results: It became known that the virus is involved in the pathogenesis of endometrial hyperplasia. It is likely that it exists in epitheliocytes not only as a “passenger”, butalso as an etiological factor. It became known that it was in complex hyperplasia with atypia that the percentage reached the highest level, which is a precancerous condition.Conclusions: Typical morphological change of the endometrium – multinucleation, multinuclearity and koilocytotic atypia in women of childbearing age with HPE – was revealed.The presence of infectious pathogens in the endometrium of patients with HPE can be regarded as one of the possible triggers for the development of hyperplastic processes.