Open AccessKOUNIS SYNDROME - ALLERGIC MYOCARDIAL INFARCTION. A CASE REPORT
Author(s) -
Olga Wajtryt,
Tadeusz M. Zielonka,
Aleksandra Kaszyńska,
Andrzej Falkowski,
Katarzyna Życińska
Publication year - 2019
Publication title -
wiadomości lekarskie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.133
H-Index - 14
eISSN - 2719-342X
pISSN - 0043-5147
DOI - 10.36740/wlek201901127
Subject(s) - kounis syndrome , medicine , myocardial infarction , acute coronary syndrome , anaphylaxis , cardiology , sensitization , chest pain , allergic reaction , tryptase , immunoglobulin e , allergy , immunology , mast cell , antibody
Kounis syndrome or allergic myocardial infarction is an acute coronary syndrome in the course of an allergic reaction. In allergic patients in response to a specific condition -nourishment, inhalation, environmental substances, drug or insect bite there is an allergic reaction involving many different cells and mediators that can cause coronary arteryspasm or initiate the process of rupture and activation of atherosclerotic plaque resulting in acute coronary syndrome. The paper describes a case of a young man with allergy topollen and confirmed sensitization to nuts, who developed a full-blown anaphylactic shock after eating the nut mix and experienced a rapidly passing acute coronary syndromewith troponin up to 4.7 μg/L. An increased concentration of tryptase (15 μg/L), total IgE (> 3,000 IU/mL) and specific anti-nut IgE (55.1 kUA/L) were found. Based on the courseof the disease and the results of allergic and cardiac tests, allergic type 1 myocardial infarction, i.e. caused by coronary artery spasm, was diagnosed. During the hospitalization,the patient’s condition improved quickly and after a few days he left the hospital without the signs of permanent damage to the heart muscle.