Open AccessPrevention of post-surgical Complications following Odontectomy in patients with Underlying Diabetes mellitus
Author(s) -
T.M. Kanishyna,
Liudmila I. Shkilniak
Publication year - 2021
Publication title -
acta balneologica
Language(s) - English
Resource type - Journals
ISSN - 2082-1867
DOI - 10.36740/abal202103107
Subject(s) - medicine , fibrin , diabetes mellitus , regeneration (biology) , wound healing , platelet rich fibrin , surgery , angiogenesis , dentistry , immunology , endocrinology , biology , microbiology and biotechnology
Aim: Purpose of the study. The study was dedicated to assessment of the effect of photon physiotherapeutic therapy combined with the use of PRF clot on the course of regeneration processes in a socket of extracted tooth in DM patients.materials and methods: Thirty patients with confirmed diabetes mellitus aged 40 - 60 referred to the Pirogov Memorial Clinical Hospital (Vinnytsia) that required tooth extraction were engaged in the study. Patients were assigned into two groups: Group I patients with spontaneously healed post-extraction wounds, and Group II patients subjected to physiotherapy in combination with the PRF. The physiotherapeutic effect was achieved by using a multispectral photon physiological system. Platelet-rich fibrin (PRF) was produced immediately before tooth extraction from the patients` venous blood. The efficacy of the photon physiotherapeutic therapy combined with the use of PRF clot was studied by the morphological methods.Results: The study of pathomorphological features of the post-extraction wound regeneration revealed differences in patients of Groups I and II. In Group II patients, the treatment was characterized by an anti-inflammatory effect (less abundant inflammatory infiltrate with fewer polymorphonuclear leukocytes in bioptic samples), accelerated regeneration process, as evidenced by a larger number of fibroblasts on Day 3 and Day 7 of follow-up, and faster development of fibrous structures in the granular tissue. Group II patients demonstrated earlier post-extraction wound epithelialization and more active angiogenesis.Conclusions: The study of pathomorphological features of post-extraction wound regeneration proved the therapeutic efficacy of the photon effect combined with the transport of PRF to the extracted tooth socket in two DM patient groups (Group I patients with spontaneously-healed post-extraction wounds, and Group II patients subjected to physiotherapy in combination with PRF).