Open AccessFeatures of lymphocytes during programmed cell death in patients with atopic bronchial asthma
Author(s) -
Y V Pinchuk,
A C Vodu,
И Г Мустафин,
Abramova Zi
Publication year - 2009
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja870
Subject(s) - flow cytometry , apoptosis , programmed cell death , asthma , pathogenesis , disease , cell , immunology , incubation , lymphocyte , significant difference , medicine , biology , pathology , genetics , biochemistry
Background. To establish features of programmed cell death of lymphocytes depending on disease severityscore.Methods. The morphology of lymphocytes was investigated with a method of electronic microscopy. Apoptoticcells were defined by flow cytometry.Results. We have revealed lymphocytes morphological difference between asthmatics and normal donors. Alsowe found out the difference between number of cells during the incubation process.Conclusion. These findings can promote deeper understanding of the disease pathogenesis.