Open AccessTHE IMPORTANCE OF EARLY ALLERGIC RHINITIS DIAGNOSIS IN THE PREVENTION OF IT’S COMPLICATIONS
Author(s) -
А В Соболев,
А В Соболев,
О В Аак,
Аак Олег Владимирович
Publication year - 2012
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja741
Subject(s) - medicine , sensitization , allergy , dermatology , dust mites , immunoglobulin e , oral allergy syndrome , eosinophilia , immunology , allergen , antibody
Background. Determination of prevalence of allergic rhinitis in patients with an allergy in the practice of an allergist, identification of the range of sensitization to common allergens in patients of different age groups, demonstration of the early diagnosis importance. Materials and methods. Determination of specific IgE in serum by MAST-HLA panels (36 allergens, Russian Panel IV, Hitachi Diagnostics, USA) was performed for 610 patients with rhinitis. For 269 of them a comprehensive clinical examination including cytological, bacteriological and mycological study of nasal swab was carried out. Results. Allergic rhinitis was diagnosed in 55,9% of the patients, infectious rhinitis was found in 28,7%, non-allergic rhinitis with eosinophilia syndrome is set in 6,1% of individuals. IgE to pollen was present in 53,9% of cases, to house dust— in 45,0% to house dust mites — in 29,0%, to mold allergens — in 14,5%. The frequency of children sensitization com -pared with adults to dog’s epithelium was higher by 1,4 times, the cat’s epithelium — by 1,3 times, to cockroaches — by 1,8 times, to house dust mites — by more than 2-fold, to food — by 2—3-fold. The clinical case demonstrates the importance of early diagnosis of disease. The choice of medicines for treatment was discussed. Conclusion. Given that the debut of allergic rhinitis in most of the examined patients occurred in childhood, the early examination of allergy in children is reasonable for the purpose of adequate therapy.