Open AccessAssessment of Rosaceae sensitisation diagnostics in allergic children
Author(s) -
А Н Пампура,
А Н Пампура,
N G Konjukova,
Н. Г. Конюкова,
Е С Феденко,
Е С Феденко,
A I Havkin,
А.И. Хавкин,
Т С Окунева,
Т С Окунева
Publication year - 2012
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja732
Subject(s) - rosaceae , sensitization , pear , immunoglobulin e , medicine , immunology , population , allergy , biology , botany , antibody , environmental health
Background. Sensitization to the fruits of the family Rosaceae is widespread in children population, but its diagnostics is often difficult. Methods. The study included 190 children with suspected allergy to the fruit family of Rosaceae. Results. The presence of sensitization was found in 148 patients. Qualitatively, the results of in vitro and in vivo tests with allergens differed approximately one third of cases. Among children with sensitization to the fruits of a family Rosaceae specific IgE to rBet v 1 was identified approximately in 3/4, rPru p 3 — in 2/3, rBet v 2 — in 1/5 of patients. Conclusion. The results indicate a high informative determination of specific IgE (ImmunoCap, Phadia AB) to the fruits of Rosaceae (apple, pear, peach) and a recombinant allergens (rBet v 1, rBet v 2, rPru p 3).