PHENOTYPES AND ENDOTYPES OF BRONCHIAL ASTHMA: FROM PATHOGENESIS AND CLINICAL FEATURES TO THERAPY | Zendy

О М Курбачева | Zendy; К С Павлова | Zendy

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PHENOTYPES AND ENDOTYPES OF BRONCHIAL ASTHMA: FROM PATHOGENESIS AND CLINICAL FEATURES TO THERAPY

Author(s) -

О М Курбачева,

К С Павлова

Publication year - 2013

Publication title -

russian journal of allergy

Language(s) - English

Resource type - Journals

eISSN - 2686-682X

pISSN - 1810-8830

DOI - 10.36691/rja596

Subject(s) - asthma , medicine , disease , etiology , intensive care medicine , phenotype , pathogenesis , clinical phenotype , immunology , bioinformatics , pathology , biology , genetics , gene

Questions of bronchial asthma heterogeneity, approaches to allocation of various phenotypes on the basis of clinical signs, biological and genetic markers and endotypes taking into account an etiology and pathophysiology of the disease are considered in the article. Allocation of phenotypes / endotypes promote the best understanding of essence of a disease and it is expedient for development of an individual approach to therapy as some options of a current OH can differ the resistant answer to standard treatment.

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