Open AccessTreatment of itch in allergic dermatoses
Author(s) -
Yu. N. Perlamutrov,
Yu. N. Perlamutrov,
K. B. Olkhovskaya,
К. Б. Ольховская
Publication year - 2014
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja571
Subject(s) - antihistamine , itching , histamine , medicine , dermatology , pathophysiology , histamine h1 receptor , histamine antagonists , allergic inflammation , mediator , epidermis (zoology) , histamine h1 antagonists , antipruritic , allergy , immunology , receptor , pathology , pharmacology , antagonist , anatomy
Pruritus is one of the most frequent symptoms in different skin diseases. Pathophysiology of pruritus has been insufficiently studied, but to this day it is considered that the main mediator of itch is histamine. Given the important role of histamine and the location of itch receptors in the superficial layers of the epidermis, the optimum is to use a topical antihistamine. The unique properties of dimethindene (Fenistil) provides rapid elimination of symptoms of itching and inflammation in allergic dermatoses.