Open AccessBRONCHIAL ASTHMA AND SMOKING: CLINICAL FEATURES AND DIAGNOSTICS
Author(s) -
М С Блинчикова,
А. В. Жестков
Publication year - 2014
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja492
Subject(s) - asthma , medicine , disease , immunology
Background. Improvement of the results of diagnostics and optimization of treatment of adult patients with bronchial asthma on the basis of clinical, immunological and microbiological features of the disease. Methods. The study included 150 patients with bronchial asthma at the age from 18 till 65 years old (the average age - 51,8 years old). Results. It was proven, that smoking patients with bronchial asthma had upgraded levels of the inducing inflammation cytokines and reduced concentration of antiinflammatory IL-10. These changes were more expressed in a long lasting active smoking patients. Conclusion. The smoking patients had the changes of the immunological profile in combination with the more serious course of asthma compared to the nonsmoking patients.