
The case of systemic mastocytosis in the practice of the allergist-immunologist
Author(s) -
Л Г Хлудова,
T N Myasnikova,
Т С Романова,
Т В Латышева
Publication year - 2015
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja435
Subject(s) - anaphylaxis , systemic mastocytosis , urticaria pigmentosa , medicine , anaphylactoid reactions , cutaneous mastocytosis , dermatology , allergy , drug allergy , disease , immunology , pathology
Mastocytosis is a disease caused by excessive proliferation of mast cells, and it can lead to anaphylactoid reactions. Different mechanisms are involving in the development of anaphylactoid and anaphylactic reactions, however, these reactions have a similar clinical picture. Therefore, patients with mastocytosis can get into the field of view of an allergist-immunologist with suspects insect, food, drug allergy or anaphylaxis of unknown origin. It’s important not only to suggest the correct diagnosis, but also to give the patient the recommendation to reduce the risk of life-threatening reactions. In this article the case of systemic mastocytosis without skin manifestations, which has been regarded for a long time by physicians as drug hypersensitivity is considered.