Open AccessMucosal immune system: the regulatory action of probiotics
Author(s) -
N. Astafieva,
I. Gamova,
E N Udovitchenko,
I. Perfilova,
Denis Kobzev,
Irina Michailova
Publication year - 2015
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja423
Subject(s) - immune system , biology , receptor , action (physics) , gene , immunology , microbiology and biotechnology , computational biology , genetics , physics , quantum mechanics
The evidence of the beneficial effects of dairy products on the intestinal microflora was given for the first time in 1908 by I.I. Mechnikov in the famous article «A few words about the sour milk». Since that time probiotics - the living microorganisms for regulation of intestinal microbiota are the case of interest. Interactions between the probiotics and macroorganism are very complex and include a network of genes receptors, signaling molecules and a variety of other factors that determine the natural course of the disease.