Open AccessThe correction of epidermal barrier dysfunction in atopic dermatitis patients
Author(s) -
O G Elisyutina,
О В Штырбул,
E N Zemskaya
Publication year - 2016
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja386
Subject(s) - filaggrin , atopic dermatitis , medicine , dermatology , skin barrier , pathogenesis , immune dysfunction , immunology , disease , atopy , immune system , allergy , pathology
Atopic dermatitis is chronic inflammatory multifactorial disease, which has genetic disorders, immune mechanisms of development and is under the ainfluence of a combination of exogenous and endogenous factors. Recently a leading role of the epidermal barrier dysfunction in the pathogenesis of atopic dermatitis was shown. The article presents data about emollient for skin care efficacy - Cetaphil® RESTORADERM, which consists of preceramides and filaggrin breakdown products in complex treatment of atopic dermatitis patients.