AGE-RELATED PATHOGENTIC SPECIFICITY OF CYTOKINE PROFILE IN ATOPIC DERMATITIS PATIENTS | Zendy

Е Е Варламов | Zendy; O G Elisyutina | Zendy; Т В Виноградова | Zendy; E S Fedenko | Zendy; А Н Пампура | Zendy

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AGE-RELATED PATHOGENTIC SPECIFICITY OF CYTOKINE PROFILE IN ATOPIC DERMATITIS PATIENTS

Author(s) -

Е Е Варламов,

O G Elisyutina,

Т В Виноградова,

E S Fedenko,

А Н Пампура

Publication year - 2016

Publication title -

russian journal of allergy

Language(s) - English

Resource type - Journals

eISSN - 2686-682X

pISSN - 1810-8830

DOI - 10.36691/rja358

Subject(s) - eotaxin , atopic dermatitis , medicine , cytokine , immunology , chemokine , dermatology , inflammation

Background. In this article the results of own research of the cytokine profile in atopic dermatitis (AD) adults and children depending on age are provided. Materials and methods. 88 patients with AD (54 children aged from 1 year to 16 years old and 24 adults aged from 21 years to 56 years old) were included in the study. Cytokine profile of a number of cytokines: IL-4, IL-5, IL-22, IL-31, IL-33, and transforming growth factor TGFβ1, eotaxin, eotaxin2 was examined. Results. Significant differences in IL-22, CC chemokines (eotaxin and eotaxin-2) and TGFβ levels depending on the age and severity of atopic dermatitis were found.

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