Open AccessFeatures of immunopathogenesis of atopic dermatitis
Author(s) -
Olga Olegovna Pobezhimova,
Побежимова Ольга Олеговна,
А. В. Жестков,
Жестков Александр Викторович,
О С Сидорова,
Сидорова Ольга Сергеевна,
В В Кулагина,
Кулагина Вера Викторовна
Publication year - 2020
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja1357
Subject(s) - atopic dermatitis , pathogenesis , medicine , immunology , dermatology , disease , immune system , allergy , immune dysfunction , pathology
Atopic dermatitis is one of the most common allergic diseases with severe course, which affects the skin. This disease is genetically determined and has a chronic course. Atopic dermatitis is also one of the commonest diseases (between 20% and 40% of all skin disorders) and affects patients of both sexes across the globe. Such high rate of morbidity, onset in early childhood, often continuous relapsing course and a trend toward gradual increase of tolerance to traditional therapies makes the issue of detalization of pathogenesis of atopic dermatitis particularly topical. Immune cells play one of the major roles in the pathogenesis of atopic dermatitis. This article will systematically review the main available to date information on participation immune cells in the pathogenesis of atopic dermatitis.