Actual directions and medical and social problems in clinical allergology: allergens, hidden allergens, food additives, GMO

Global problems affecting all the human kind also affect healthcare, including clinical allergology and immunology, especially in the changing climate and environment conditions. The consequence of these problems is the increase of allergic diseases and immune deficiencies prevalence and severity in the world, as well as the increase in the number and role of «hidden» and the emergence of «new» allergens, the increase in the consumption of food additives, genetically modified foods, etc. In a changing climate and environmental degradation, there is a change in the concentration and role of air pollutants, a change in the composition and properties of pollen as well as household, epidermal, infectious and insect allergens. Climate change and environmental degradation are one of the reasons for the increase of the allergic diseases onset among the elderly and seniors, and for the negative impact on the development mechanisms, course and prognosis of allergy - and immunopathology. All this requires an integrated approach to solve the interrelation problems of health, ecology, climate, etc., and the creation of a global strategy program for new therapeutic approaches and prevention of allergic diseases and immunodeficiency states.