Open AccessAllergic manifestations in patients with sensitization to cat allergens
Author(s) -
Erwin Baß,
Irina Tuzankina
Publication year - 2018
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja108
Subject(s) - sensitization , medicine , allergen , atopic dermatitis , dermatology , allergy , food allergens , immunology , allergic dermatitis , respiratory tract , respiratory system
Relevance. Cats and dogs are the most popular pets in many countries, what leads to a high and widespread prevalence of their allergens and increase of sensitization to animal allergens with tendency of changing the dominant profile of sensitization with the predominance of the major cat allergen. The purpose of this study was to assess the severity of allergic rhinitis and its combination with other forms of allergic diseases in children sensitized to cat allergens. Materials and methods. Under our supervision there were 228 children aged 3-16 years old living in the cities of the Sverdlovsk region. Evaluation of the sensitization spectrum was carried out according to the results of prick tests and the level of sIgE by immunofluorescence method. Results. All children had manifestations of persistent allergic rhinitis. In 42.1% (n=96) of cases the upper and lower respiratory tract comorbidities were detected, in 16.6% (n=38) - manifestations of atopic dermatitis. In 65.4% (n=149) of children the total level of points on the SFAR scale was