Open AccessImmune status of the workers of technogenic-excited environment manufacture and of population living in this territory
Author(s) -
I. V. Oradovskaya,
N A Leyko,
B V Feoktistov,
M A Oprishchenko,
Л В Лусс,
М Ф Никонова,
В В Иванов,
V M Zabelov,
I V Oradovsraya,
LA Leyko,
VV MA Eeoktistov,
Л В Лусс,
М Ф Никонова,
В В Иванов,
V M Zabelov
Publication year - 2009
Publication title -
rossijskij allergologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2686-682X
pISSN - 1810-8830
DOI - 10.36691/rja1031
Subject(s) - immune system , immune status , population , immunology , lymphocyte , cd8 , phagocytosis , medicine , environmental health
Background. To study the influence of technogenic-excited environment manufacture on clinical and immuneparameters of employees and population living in the territory of its influence.Methods. The analysis of frequency of clinical features of immune dysfunction with clinical, immunolologicaland allergological examination was carried out. 689 persons were examined: 474 - the personnel of industrialcomplex, 215 - the population which is not working at industrial complex.Results. Clinical signs of immune dysfunction during 2 year follow-up period were established in 77,3% ofpopulation group. The immune parameters in all groups during 2 year follow-up period in comparison withthose during 1 year follow-up period showed the decreasing of number of leukocytes, T-lymphocytes, CD4+T-lymphocytes as well as immunoregulative index. It was defined dissociation in level of NK-cells, expressed indecreasing of absolute values of CD16+ lymphocytes and increasing of their percentage and increasing of CD8+T-lymphocytes, B-lymphocytes and phagocytosis parameters.