Open AccessRHINO-ORBITO-CEREBRAL MUCORMYCOSIS (BLACK FUNGUS) IN COVID 19 PATIENTS
Author(s) -
Keshav Gupta
Publication year - 2021
Publication title -
up state journal of otorhinolaryngology and head and neck surgery
Language(s) - English
Resource type - Journals
ISSN - 2321-3450
DOI - 10.36611/upjohns/volume9/issue2/5
Subject(s) - mucormycosis , medicine , amphotericin b , diabetes mellitus , surgery , dermatology , antifungal , endocrinology
BACKGROUNDMucormycosis (Black fungus) is a designated as arare, rapidly progressive fatal disease ofimmunocompromised caused by saprophyticfungus of family mucorales. Early diagnosis withprompt medical and surgical treatment is the onlytool available. Rhino-orbito-cerebral is the mostcommon subtype. In India we saw a sudden rise inmucormycosis cases during second wave ofCOVID 19. This necessitated a systematic review ofepidemic of mucormycosis in COVID 19.METHODSA Retrospective multi-centric study was conductedat various Government and Private Hospitals ofWestern UP comprising of 51 cases of Rhino-orbitocerebral mucormycosis with present or recentCOVID19 positive status presenting to us during14th April 2021- 31st May 2021.RESULTEither Type2 Diabetes Mellitus or history of recentuse of steroids in high doses was present in all thepatients. Contribution of virulence of the Deltastrain B1.617.2 is significant. FESS with sino-nasaldebridement contributes significantly towardsmortality reduction and cost of total treatment bysignificantly reducing days of LiposomalAmphotericin B therapy.CONCLUSIONEarly diagnosis with prompt medical and surgicalmanagement along with blood sugar control andavoiding use of high dose of steroids remain to keyto mortality and morbidity reduction.Keywords: Black fungus, mucor, mucormycosis,rhino-orbito-cerebral, causes, treatment, covid 19, India, sugar, steroids, steam, oxygen, surgery