Open AccessThe Efficacy of Surgery for Supra-Tentorial Gliomas in Preventing Seizures
Author(s) -
Muhammad Tariq,
Adnan Munir,
Mushtaq Ahmad Mian,
Muhammad Farooq,
Irfan Jan,
Faiqa Filza
Publication year - 2022
Publication title -
pakistan journal of neurological surgery
Language(s) - English
Resource type - Journals
eISSN - 2409-5567
pISSN - 1995-8811
DOI - 10.36552/pjns.v26i1.653
Subject(s) - neurosurgery , medicine , temporal lobe , frontal lobe , epilepsy , occipital lobe , magnetic resonance imaging , lobe , glioma , neuroimaging , parietal lobe , radiology , surgery , pathology , psychiatry , cancer research
Objectives: The study examined the surgical outcome of supratentorial gliomas in terms of improvement in seizures in patients who presented to a tertiary care institution.Material and Methods: A descriptive case series was conducted in Neurosurgery Department at Northwest General Hospital & Research, Peshawar. Patients (n = 95) with supratentorial gliomas with seizures between 18 – 70 years were included. Supratentorial gliomas were diagnosed by neuroimaging as MRI brain with contrast, diffusion-weighted, Fluid-attenuated inversion recovery, and magnetic resonance spectroscopy. The patient was observed for seizures postoperatively. Data was stratified for age and gender.Results: The majority of patients (36.8%) were in 41 – 50 years. 55.78% of patients were males whereas 44.21% of patients were females. 42 (44.21%) involved the frontal lobe, 16 (16.84%) involved the parietal lobe, 26 (27.36%) involved the temporal lobe, and 11 (11.57%) patients involved the occipital lobe. According to Engel’s classification, 53 patients were in class I, 16 in class II, 10 in class III, and 5 in class IV. 84 (88.42%) experienced post-op seizure reduction. An insignificant association was found with the seizure improvement (yes/no) with different age groups and gender.Conclusion: The frontal lobe was the most prevalent location for supratentorial gliomas. After surgery, a large proportion of patients improved in terms of seizure management.Keywords: Seizures, Supratentorial gliomas.