
Incidence of Epilepsy and Drug Dependence after Post Traumatic Contusions Managed Conservatively
Author(s) -
Faiq Sheikh,
Rabia Saleem,
Jamal Abdul Nasir,
Ahmed S. Sultan,
Abuzar Rauf,
Muhammad Anwar Chaudhary
Publication year - 2021
Publication title -
pakistan journal of neurological surgery
Language(s) - English
Resource type - Journals
eISSN - 2409-5567
pISSN - 1995-8811
DOI - 10.36552/pjns.v25i2.560
Subject(s) - medicine , incidence (geometry) , observational study , epilepsy , population , surgery , pediatrics , prospective cohort study , psychiatry , physics , environmental health , optics
contusions managed conservatively.
Material and Methods: A prospective observational study was carried out in, Punjab Institute of Neurosciences, Lahore. A total of 97 patients, from 15-65 years, who were diagnosed with cerebral contusions and being managed conservatively were enrolled from July 2019 to December 2019. They were followed-up for 12 – 18 months.
Results: A total of 23% patients developed early post-traumatic seizures (PTS) and 11% of patients developed late post-traumatic seizures with mild to moderate brain injury.6% of patients with early PTS used antiepileptic drugs (AED) for at least three months during follow up and 7% with late PTS used AED. 8% of patients developed late PTS without any early PTS. The results of our study show that among 23% early PTS and 11% late PTS only 3 % actually required to use AED for at least 6months. To prevent this, 3% of the population 44% were using AED supplementary.
Conclusion: In our study, the incidence of early and late PTS is comparable to the other studies. The non-judicious use of the anti-epileptic drug is common in our country which leads to an increase in the risk of drug resistance and cost-intensive for poor patients in developing countries as prophylactic and excessive use of anti-epileptics does not affect the PTE.