Open AccessAsthma in Pregnancy: Mechanism and Clinical Implication
Author(s) -
Triya Damayanti,
Sri Pudyastuti
Publication year - 2020
Publication title -
jurnal respirologi indonesia
Language(s) - English
Resource type - Journals
eISSN - 2620-3162
pISSN - 0853-7704
DOI - 10.36497/jri.v40i4.125
Subject(s) - pregnancy , asthma , medicine , exacerbation , fetus , hormone , hypoxia (environmental) , placenta , asthma exacerbations , pulmonary function testing , obstetrics , genetics , organic chemistry , oxygen , biology , chemistry
Asthma in pregnancy can influence clinical status of an asthma patient. Study showed that one third of asthma patients were worsening, one third stable and one third improving. During pregnancy, lung function, ventilation pattern and gas diffusion are influenced by biochemistry (hormonal) and mechanic. Mechanism in pregnancy with asthma including hypoxia, inflammation, corticosteroids therapy, history of exacerbation, smoking mother and changes in placenta function. Hormonal status during pregnancy is different with non-pregnancy woman which hormonal level changes through the pregnancy time. Those changes can influence lung function in pregnancy. Treatment of asthma in pregnancy is giving optimal asthma therapy, therefore it can improve asthma control, also the quality of life of a mother and her fetus during pregnancy.