Open AccessEvaluation of Single Verses Multiple Doses of Suxamethonium in Rigid Bronchoscopy: A Tertiary Care Hospital Study in Bangladesh
Author(s) -
Dr. Md. Rejaul Hasan,
Shawkat Mahmood,
Sayeda Begum Panna,
Dr. Md. Shamim Hossain Apel
Publication year - 2022
Publication title -
saudi journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2518-3397
pISSN - 2518-3389
DOI - 10.36348/sjm.2022.v07i03.001
Subject(s) - medicine , observational study , fasciculation , bronchoscopy , tertiary care , statistical significance , intubation , anesthesia , clinical significance , surgery
Background: Rigid bronchoscopy is frequently required in the therapeutic therapy of a wide range of tracheobronchial diseases. Suxamethonium is a common neuromuscular blocking medication used for rapid sequence tracheal intubation because of its quick onset and recovery. Objective: The objective of the study was to evaluate the effects of single vs multiple doses of Suxamethonium in rigid bronchoscopy. Methodology: This randomized cross-sectional observational study was conducted from January 2019 to December 2020 among 180 patients in a tertiary care hospital of Bangladesh. Data on certain basic parameters were obtained on the basis of the clinical records and related changes. Collected data were displayed in tabular and graphical form in terms of different parameters, and statistical analysis was conducted to observe the statistical significance. Results: In this study, we divided patients into 2 groups (Group 1: Single dose Suxamethonium, Group 2: multiple-dose Suxamethonium). Among 180 patients, a maximum (34.4%) patients were more than 50 years of age. Also, 58% were male, and 42% were female patients. Here, maximum patients (33.8%) had a cough, while minimum patients (2.7%) had chest pain. Among group 1, maximum patients (39.1%) had mild fasciculation scores and minimum patients (7.4%) had zero scores. Among group 2 patients, maximum patients (24.3%) had zero fasciculation score, and minimum patients (6.3%) had vigorous scores. According to the Copenhagen scoring system, in group 1, 47.40% of patients had an excellent outcome, and 6.65% of patients had a poor outcome. And in group 2, 74.7% of patients had a good outcome and 13.50% of patients had an excellent outcome. In both groups, maximum patients had minor bleeding, vocal cord trauma, and hypoxia. Conclusion: The findings imply that single-dose Suxamethonium was more effective in improving patient satisfaction. The intubating settings would be more pleasant if single-dose Suxamethonium was used.