Open AccessPOEMS Syndrome: A Case Report and Literature Review
Author(s) -
Imane Benbella,
Houda ElAsri,
Safaa Rifai,
Mustapha Mahmoud,
Fatima El Boukhrissi
Publication year - 2022
Publication title -
saudi journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 2518-3397
pISSN - 2518-3389
DOI - 10.36348/sjm.2022.v07i01.015
Subject(s) - poems syndrome , organomegaly , polyneuropathy , medicine , monoclonal gammopathy , disease , peripheral neuropathy , pathology , poetry , dermatology , pediatrics , monoclonal , immunology , endocrinology , literature , diabetes mellitus , art , antibody , monoclonal antibody
POEMS syndrome is a rare paraneoplasic syndrome associated to a plasma cell proliferative disorder, which is characterized by the presence of peripheral neuropathy (P), organomegaly (O), endocrinopathy (E), monoclonal gammopathy (M) and skin change (S). Because of the rarity of this disease, the small number of cases described in the literature and the polymorphism of the clinical manifestations, the diagnosis of POEMS syndrome remains difficult. The prognosis of the disease is related to the early onset of specific treatment. We hereby present a clinical case of POEMS syndrome in a 41-year-old woman revealed by a polyneuropathy, in order to highlight the diagnostic problems and to raise awareness of this syndrome.