Open AccessDetermination of Antibiotic Susceptibility Profile of some Enterobacteria Isolated from Respiratory Tract Infection Patients Attending some Tertiary Hospital in Kano, Northern Nigeria
Author(s) -
Hauwa M. Aliyu,
M Yusha’u,
Dalha W. Taura,
Muhammad Ali,
Shamsu I. Abdullahi
Publication year - 2022
Publication title -
scholars bulletin
Language(s) - English
Resource type - Journals
eISSN - 2412-9771
pISSN - 2412-897X
DOI - 10.36348/sb.2022.v08i03.005
Subject(s) - ciprofloxacin , ampicillin , microbiology and biotechnology , antibiotics , ceftazidime , sulfamethoxazole , gentamicin , antibiotic resistance , trimethoprim , ceftriaxone , biology , medicine , bacteria , pseudomonas aeruginosa , genetics
Bacterial antibiotic resistance is a type of drug resistance whereby some sub-populations of bacterial species are able to survive after exposure to one or more antibiotics. The study was aimed to determine the antibiotic susceptibility profile of some enterobacteria from respiratory tract infection (RTIs) patients attending some tertiary Hospital in Kano, Northern Nigeria. A total of one thousand and ninety six (1096) isolates were collected. Isolates were subjected to Gram staining, motility test, biochemical characterization and further examined using Microgen TM Gram negative Identification A (Microgen GN ID A) system. Susceptibility of the isolates to some commonly used antibiotics was determined using the disc diffusion method. The result showed that various Enterobacteriaceae isolates confirmed were Pantoae agglomerans 250 (53.53%) being the most occurring followed by Klebsiella spp 160 (34.26%) and then Escherichia coli 57 (12.21%) respectively. The antibiotic resistance pattern of the isolates showed that the highest resistance level was recorded for Ampicillin (78%), followed by Amoxycillin (72%), Ceftazidime (42%). There is also a significant level of resistance to Sulfamethoxazole trimethoprim (36%), Ceftriaxone (28%) and chloramphenicol (24%). Lower resistance levels were observed against Gentamicin (8%) and Ciprofloxacin (10%). It is concluded that there is significant level of antibiotic resistant of some isolates from respiratory tract infection (RTIs) patients.