Open AccessHaematuria: A Rare Manifestation of Glanzmann Thrombasthenia
Author(s) -
Mrabti Mohammed,
Larbi Hamedoun,
Ilyas Hassan,
Melang Mvomo Thomas Alexis,
Younes Boukhlifi,
Tetou Mohamed,
Omar Jendouzi,
A. Ameur,
Alami Mohamed
Publication year - 2022
Publication title -
scholars journal of medical case reports
Language(s) - English
Resource type - Journals
eISSN - 2347-9507
pISSN - 2347-6559
DOI - 10.36347/sjmcr.2022.v10i04.006
Subject(s) - glanzmann's thrombasthenia , thrombasthenia , medicine , refractory (planetary science) , platelet , recombinant dna , platelet transfusion , recombinant factor viia , surgery , gastroenterology , platelet aggregation , biochemistry , physics , chemistry , astrobiology , gene
Summary: Glanzmann Thrombasthenia (GT) is a congenital thrombopathy characterised by bleeding manifestations that are sometimes severe. Treatment is based on platelet transfusions during bleeding. We report a case of TG revealed by haematuria and which presented a severe bleeding syndrome refractory to transfusions. Treatment with injections of recombinant activated factor VII was necessary. This case illustrates the value of using recombinant activated factor VII in TG in case of antiplatelet alloimmunisation or in case of lack of response to platelet transfusions.