Open AccessChronic Hyperglycemia as a Predictor of Acute Kidney Injury Requiring Continuous Renal Replacement Therapy (CRRT) in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery
Author(s) -
M. Azizan Petra,
M. Ezani Taib,
I. F. Gaafar
Publication year - 2022
Publication title -
scholars journal of applied medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2347-954X
pISSN - 2320-6691
DOI - 10.36347/sjams.2022.v10i04.034
Subject(s) - medicine , renal replacement therapy , acute kidney injury , incidence (geometry) , retrospective cohort study , copd , diabetes mellitus , artery , coronary artery bypass surgery , surgery , physics , optics , endocrinology
Background: Chronic Hyperglycaemia with HBA1C is an indicator affecting postoperative care after CABG. AKI is one of the frequent postoperative complications after CABG, impacting short- and long-term outcomes. This research project will investigate the association between chronic hyperglycemia and post operative incidence of AKI requiring CRRT in CABG patients. Methods: A retrospective study was conducted from 1st January 2016 to 31st December 2019 who underwent isolated CABG in Institut Jantung Negara, Malaysia. Patients were divided into two groups; patients who have HbA1c ≤6 and patients who have HbA1c >6. Primary outcome measured were the incidence of AKI that leads to CRRT. Secondary outcome measured were, mortality, chest reopen, length of ICU stay and total hospital stay. Results: Total of 2019 patients were included. Baseline characteristic were measured. BMI, hypertension and high cholesterol were significantly higher in the HbA1c > 6. The rest of the baseline characteristic including age, smoking status and COPD status showed no significant differences in both groups. 17 patients (1.5% p 6 group, compare to 3 patient (0.3% p 6 group at 2.3 ±3.1 days p 6 group at 8.3 ± 6.6 days p 6 was associated with higher incidence of AKI requiring CRRT. Length of ICU and post-op hospital stay were higher in the HbA1c >6 group. This finding might implicate the importance of sugar control preoperatively, especially in diabetes patients.