Open AccessQuality Control in Screening for Infectious Diseases at Blood Banks
Author(s) -
Isam Eldin Hassan Ali,
Abdelaziz M. Humd,
Manal Mostafa,
Hamza Abdallah
Publication year - 2022
Publication title -
scholars journal of applied medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2347-954X
pISSN - 2320-6691
DOI - 10.36347/sjams.2022.v10i02.022
Subject(s) - medicine , syphilis , external quality assessment , serology , human immunodeficiency virus (hiv) , intensive care medicine , immunology , antibody , pathology
Background: It has long been recognized that blood bank institutions have an obligation to not only provide a safe product for patients, but also to protect the health and welfare of their donors and their staff. Quality control procedures are indispensable to en¬sure the reliability of the results provided by labora¬tories responsible for serological screening in blood banks. International recommendations on systems of quality management classify as a top component the inclusion of two types of control: (a) internal quality control (IQC) and (b) external quality control (EQC). Methods: A total of 300 donations were collected and screened for HBV, HCV, syphilis and HIV-1 using the enzyme inked immune sorbent assay. All initially reactive (IR) samples were retested in triplicate and, if repeatedly reactive (RR), consider as reactive. Results: The results showed that the sensitivity and specificity of the QCs in anti-B testing were 100% and 98.7%, respectively. The sensitivity and specificity of the QCs in testing, viral screening were all 99%. Therefore our QC products and methods are highly sensitive, specific, and reliable. Our study paves the way for the establishment of a uniform and standardized QC method for pre-transfusion compatibility testing in Sudan and other parts of the world. Conclusion: The implementation of screening for three viruses has improved blood safety in Sudan.