Open AccessNeurofibromatosis Type 1 and Pheochromocytoma: Case Report
Author(s) -
Mohamed Lemine Ahmed Salem,
Jalila Ters,
Hicham El bouhadouti,
El bachir Benjelloun,
Abdelmalek Ousadden,
Khalid Ait Taleb,
Ouadii Moaquit
Publication year - 2021
Publication title -
sas journal of surgery
Language(s) - English
Resource type - Journals
ISSN - 2454-5104
DOI - 10.36347/sasjs.2021.v07i11.013
Subject(s) - neurofibromin 1 , neurofibromatosis , pheochromocytoma , medicine , neurofibromatosis type i , pathology , cancer research
Neurofibromatosis type 1 (NF1) is a genetic disorder associated with neurofibromin 1 (NF1) gene mutation, which predisposes for various benign and malignant tumors. Some of these tumors that frequently observed in NF1 are pilocytic astrocytomas, gastrointestinal stromal tumors, pheochromocytomas and juvenile myelomonocytic leukemia. Pheochromocytomas account for 4% of incidentally discovered adrenal tumors and 0.1 to 0.2% of hypertensive patients. Neurofibromatosis type 1 is a rare cause of pheochromocytoma. We discuss through this case and a review of the literature.