Open AccessAcquired Factor VII Deficiency Presenting as Cardiac Tamponade: A Case Report
Author(s) -
Yasmina Malky,
Zainab Boudhar,
Khaoula Bourzeg,
Mohammed El Jamili,
Dounia Benzeroual,
Saloua El Karimi,
Mustapha El Hattaoui
Publication year - 2022
Publication title -
sas journal of medicine
Language(s) - English
Resource type - Journals
ISSN - 2454-5112
DOI - 10.36347/sasjm.2022.v08i02.003
Subject(s) - medicine , bleeding diathesis , fresh frozen plasma , asymptomatic , factor vii , cardiac tamponade , gastroenterology , pericardiocentesis , tamponade , surgery , pediatrics , coagulation , platelet
FVII (factor VII) is vitamin K-dependently synthesized in the liver. Hepatopathies, vitamin K deficiency, or use of vitamin K antagonists are the causes of acquired deficiency. Other types of acquired FVII deficiencies are rare. However, based on literature the incidence might be underestimated. The clinical manifestation of acquired FVII deficiency varies greatly in severity; asymptomatic course as well as severe life-threatening bleeding diathesis and fatal bleedings have been described. In this case report, we discuss a unique presentation of a 79-year-old male who was found to have cardiac tamponade revealing a severe acquired factor VII deficiency. A discordance between a prolonged PT and a normal aPTT was found in the biology lab report. And the diagnosis was confirmed by obtaining a factor VII activity assay. His management involved correction of his factor VII deficiency with fresh frozen plasma and pericardiocentesis.