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Dithymoquinone Prevents Preeclampsia and Conserves Foetal Health: A Perspective Study
Author(s) -
Mosab Nouraldein Mohammed Hamad
Publication year - 2022
Publication title -
south asian research journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2664-6749
pISSN - 2664-4142
DOI - 10.36346/sarjps.2022.v04i02.003
Subject(s) - preeclampsia , miscarriage , pregnancy , fetus , medicine , histamine , obstetrics , abortion , placenta , physiology , endocrinology , biology , genetics
Dithymoquinone is a poorly studied carbonyl polymer of thymoquinone component of black cumin seeds. It suppresses release of histamines and improves clearance of cortisol in the liver and maintains the strength of placental aryl hydrocarbon receptors. Furthermore, we hypothesized that the low percentage of it in black seeds and its slow reduction make it safe for both the mother and her foetus. As many studies suggest, high levels of both histamine and cortisol are associated with preeclampsia, miscarriage, still birth and preterm delivery. We hypothesized that administration of dithymoquinone during pregnancy will prevent pregnancy complications, certainly preeclampsia and maintain the foetus’s life. Experimental research is required to know more about the role of dithymoquinone in maternal and foetal health.

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