Open AccessDrug interactions
Author(s) -
Zainub Jooma
Publication year - 2020
Publication title -
southern african journal of anaesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.175
H-Index - 10
eISSN - 2220-1173
pISSN - 2220-1181
DOI - 10.36303/sajaa.2020.26.6.s3.2543
Subject(s) - drug , pharmacodynamics , pharmacokinetics , pharmacology , pharmaceutical drug , drug administration , medicine
Administration of multiple drugs within a short period of time is inevitable in anaesthesia practice, increasing the likelihood of drug interactions with each drug or with patients’ chronic medication. Drug interactions can be described as the pharmacological effect of one drug on another drug when administered simultaneously. The principles of these interactions may be divided into pharmaceutical, which relates to the physicochemical structure or pharmaceutical preparation of a drug; pharmacokinetic (PK), which relates to changes in drug handling in the body; or pharmacodynamic (PD) where drug activity is affected.